B. Kuropka

When less is more - A fast TurboID KI approach for high sensitivity endogenous interactome mapping

The paper compares labelling enzymes for proximity labelling experiments using CRISPR-Cas9 knock-ins, showing TurboID's effectiveness in identifying interactors and cargo proteins.

T cell interaction partners of DHHC20

This study identifies DHHC20 interaction partners in T cells, showing it interacts with Gsβ1γ2 and suggests a model for its role in palmitoylation.

Decoding of T cell immunodominance patterns by an integrated mechanistic approach

The paper identifies immunodominant CD4+ T cell epitopes for SARS-CoV-2 antigens by integrating antigen processing systems with in silico tools, revealing distinct processing mechanisms for different antigens.

Plasma proteome signature of canine acute haemorrhagic diarrhoea syndrome (AHDS)

The paper identifies plasma proteome alterations in dogs with acute haemorrhagic diarrhoea syndrome (AHDS) and finds several proteins are differentially expressed, suggesting potential biomarkers for diagnosis.

Label-free quantification LC-mass spectrometry proteomic analysis of blood plasma in healthy dogs

This study quantifies plasma proteins in healthy dogs using label-free LC-MS proteomics and compares two depletion methods for high-abundance proteins.

Population context drives cell-to-cell variability in interferon response in epithelial cells

The paper shows that population context affects cell-to-cell variability in interferon response in human intestinal epithelial cells, with edge cells being more responsive than central ones.

Mechanisms of low susceptibility to the disinfectant benzalkonium chloride in a multidrug-resistant environmental isolate of Aeromonas hydrophila

This study identifies mechanisms of resistance in an Aeromonas hydrophila strain to benzalkonium chloride using genomic and proteomic analyses.

Gene amplifications cause high-level resistance against albicidin in Gram-negative bacteria

This study identifies gene amplification as a mechanism conferring high-level resistance to albicidin in Gram-negative bacteria, validated across multiple species.

Eating in a losing cause: limited benefit of modified macronutrient consumption following infection in the oriental cockroach Blatta orientalis

This study investigates how bacterial infection affects macronutrient consumption and immunity in Blatta orientalis cockroaches, finding limited immune benefits from dietary shifts.

ADAPs intrinsically disordered region is an actin sponge regulating T cell motility

This study identifies ADAP's intrinsically disordered region as an actin sponge that regulates T cell motility by promoting actin polymerization and bundling.

Purification of functional Plasmodium falciparum tubulin allows for the identification of parasite-specific microtubule inhibitors

This study purifies functional Plasmodium falciparum tubulin and identifies parasite-specific microtubule inhibitors that selectively disrupt protozoan microtubule growth.

Antimicrobial peptide induced-stress renders Staphylococcus aureus susceptible to toxic nucleoside analogues

The paper shows that sub-lethal concentrations of the antimicrobial peptide pexiganan increase susceptibility of Staphylococcus aureus to nucleoside analogues.

Positive and negative intra-molecular modulation in a dual-cassette RNA helicase

This study shows that the inactive C-terminal cassette of Brr2 can both positively and negatively modulate the active N-terminal cassette's RNA-related activities through structural changes.