M. Andreu-Carbo

Trace Amines are Essential Metabolites for the Autocrine Regulation of β-Cell Signaling and Insulin Secretion

This study identifies trace amines (TAs) as essential autocrine signaling factors for β-cell activity and insulin secretion, showing their modulation affects intracellular Ca2+ oscillations and insulin release.

Running Kinesin-1 shapes the microtubule acetylation gradient

The paper shows that kinesin-1-induced damage sites regulate microtubule acetylation by enabling HDAC6 entry, while TAT1 acetylation is independent of kinesin-1, leading to an exponential acetylation gradient in cells.

The effect of motor-induced shaft dynamics on microtubule stability and length

This study investigates how molecular motors affect microtubule stability and length through tubulin exchange along the shaft, revealing novel insights into microtubule network regulation.

Motor usage imprints microtubule stability in the shaft

The paper shows that molecular motor activity on microtubules increases their average length and densifies the network, influencing cell polarity through dimer exchange along the shaft.