Author

M. Azam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Organism:rat· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

P. Nunes-Hasler· 2 shared A. Ahmad· 1 shared A. F. Cayron· 1 shared A.-C. Gavin· 1 shared B. R. Kwak· 1 shared C. Castelbou· 1 shared D. Starczynowski· 1 shared E. Allemann· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersCell Biology

P. Nunes-Hasler

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Author profile →

5 papers

Recent·Most cited

Enhanced intracranial aneurysm development in a rat model of polycystic kidney disease.

A. F. Cayron, S. Morel, M. Azam, J. Haemmerli, T. Aoki, P. Bijlenga, E. Allemann, B. R. Kwak

This study shows that PCK rats, a model of polycystic kidney disease, develop intracranial aneurysms more rapidly and have increased aortic dissection risk due to anatomical and vascular changes.

bioRxiv · Feb 28, 2024Pathology

Development of genetically-encoded fluorescent KSR1-based probes to track ceramides during phagocytosis

V. Girik, L. Van Ek, I. Dentand Quadri, M. Azam, M. Cruz Cobo, M. Mandavit, I. Riezman, H. Riezman, A.-C. Gavin, P. Nunes-Hasler

This study develops genetically encoded fluorescent probes based on KSR1's ceramide-binding domain to track ceramide dynamics during phagocytosis and identifies distinct behaviors of different probe variants.

bioRxiv · Sep 27, 2023 · PreprintCell Biology

The SNARE Sec22b regulates phagosome maturation by promoting ORP8-mediated PI(4)P exchange at ER-phagosome contact sites.

N. Criado Santos, S. Bouvet, F. Bermont, C. Castelbou, F. Mansour, M. Azam, F. Giordano, P. Nunes-Hasler

bioRxiv · Apr 12, 2022Cell Biology

Momelotinib is a highly potent inhibitor of FLT3-mutant AML

M. Azhar, Z. Kincaid, M. Kesarwani, T. Latif, D. Starczynowski, M. Azam

This study shows momelotinib is a potent FLT3 inhibitor effective against FLT3-mutant AML, including resistant variants, and suppresses resistance mechanisms like FLT3 ligand and cytokine signaling.

bioRxiv · Mar 18, 2021Cancer Biology

Animal model and therapeutic prospects for left ventricular hypertrophy and associated renal complication

A. Ahmad, Z. Riaz, M. A. Sattar, S. A. Khan, E. J. John, S. Arshad, S. T. A. Shah, M. A. Rafiq, R. Qamar, M. Azam

This study investigates the effects of hydrogen sulphide (H2S) and nitric oxide (NO) treatments on gene expression and physiological indices in a rat model of left ventricular hypertrophy (LVH) and associated renal complications, showing therapeutic potential of combined H2S+NO treatment.

bioRxiv · May 14, 2019 · PreprintPharmacology & Toxicology