Heme's relevance genuine? Re-visiting the roles of TANGO2 homologs including HRG-9 and HRG-10 in C. elegans
S. E. Sandkuhler, K. Youngs, O. Gottipali, L. Owlett, M. Bandora, A. Naaz, E. S. Kim, L. Wang, A. P. Wojtovich, V. A. Gupta, M. Sacher, S. J. Mackenzie
This study re-examines the role of TANGO2 homologs in C. elegans and finds that phenotypes previously linked to heme transport may instead reflect mitochondrial dysfunction and oxidative stress.
bioRxiv · Nov 29, 2023 · PreprintCell Biology