Author

M. C. Altman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Assay:flow cytometry· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Mejias· 2 shared A. O'Garra· 2 shared C. Bloom· 2 shared C. M. Graham· 2 shared D. Chaussabel· 2 shared E. Whalen· 2 shared F. Kheradmand· 2 shared G. Klintmalm· 2 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. Mejias

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Author profile →

4 papers

Recent·Most cited

Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants

J. P. Gygi, C. Maguire, R. K. Patel, P. Shinde, A. Konstorum, C. P. Shannon, L. Xu, A. Hoch, N. Jayavelu, IMPACC Network, E. K. Haddad, E. F. Reed, M. Kraft, G. A. McComsey, J. Metcalf, , Pete

This study identifies immune programs linked to COVID-19 severity and mortality through longitudinal multi-omics analysis of 1,152 hospitalized patients.

bioRxiv · Nov 3, 2023Immunology

Development and Characterization of a Fixed Repertoire of Blood Transcriptome Modules Based on Co-expression Patterns Across Immunological States

M. C. Altman, D. Rinchai, N. Baldwin, M. Toufiq, E. Whalen, M. Garand, B. A. Kabeer, M. Alfaki, S. Presnell, P. Khaenam, A. A. Benitez, F. Mougin, P. Thebault, L. Chiche, N. Jourde-Chiche, , D. Chaussabel

The paper develops a fixed repertoire of blood transcriptome modules based on co-expression patterns across immunological states to provide a stable framework for analyzing and interpreting blood transcriptome data.

bioRxiv · Apr 28, 2020Immunology

A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring

M. C. Altman, N. Baldwin, E. Whalen, T. Al-Shaikhly, S. Presnell, P. Khaenam, V. H. Gersuk, L. Chiche, N. Jourde-Chiche, T. Phillips, G. Klintmalm, A. O'Garra, M. Berry, C. Bloom, R. J. Wilkinson, , D. Chaussabel

The paper develops a targeted transcriptome fingerprinting assay using modular transcriptional repertoires to assess immune functions in clinical settings.

bioRxiv · Mar 24, 2019 · PreprintImmunology

Ruxolitinib partially reverses functional NK cell deficiency in patients with STAT1 gain-of-function mutations

A. Vargas Hernandez, E. M. Mace, O. Zimmerman, C. Zerbe, A. Freeman, S. Rosenzweig, J. W. Leiding, T. Torgerson, M. C. Altman, E. Schussler, C. Cunningham-Rundles, I. K. Chinn, I. C. Hanson, N. L. Rider, S. M. Holland, , L. R. Forbes

This study shows that ruxolitinib partially restores NK cell function in STAT1 GOF patients by reducing STAT1 phosphorylation and improving cytotoxic activity.

bioRxiv · Jun 28, 2017Immunology