Author

V. H. Gersuk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:database / resource· 1

Frequent Co-Authors

A. Arnett· 1 shared A. E. Wiedeman· 1 shared A. F. Shamji· 1 shared A. K. Savage· 1 shared A. Mejias· 1 shared A. O'Garra· 1 shared B. Khor· 1 shared C. Acosta-Vega· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperImmunology

A. Arnett

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Author profile →

3 papers

Recent·Most cited

A simple strategy for sample annotation error detection in cytometry datasets

M. Smithmyer, A. E. Wiedeman, D. A. G. Skibinski, A. K. Savage, C. Acosta-Vega, S. Scheiding, V. H. Gersuk, S. A. Long, J. H. Buckner, C. Speake

The paper detects sample annotation errors in cytometry data by comparing HLA allele expression with longitudinal and qPCR data, identifying mismatches in 2.4% of samples.

bioRxiv · Oct 26, 2021Immunology

The CDK8 inhibitor DCA promotes a tolerogenic chemical immunophenotype in CD4+ T cells via a novel CDK8-GATA3-FOXP3 pathway

A. Arnett, K. G. Moo, K. J. Flynn, T. B. Sundberg, L. Johannessen, A. F. Shamji, N. S. Gray, T. Decker, V. H. Gersuk, D. E. Levy, I. J. Marie, Z. S. Rahman, Y. Zheng, P. S. Linsley, R. J. Xavier, B. Khor

The paper identifies DCA as a CDK8 inhibitor that induces a tolerogenic immunophenotype in CD4+ T cells through a novel CDK8-GATA3-FOXP3 pathway, promoting Treg and Th2 differentiation while inhibiting Th1 and Th17.

bioRxiv · Mar 4, 2021 · PreprintImmunology

A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring

M. C. Altman, N. Baldwin, E. Whalen, T. Al-Shaikhly, S. Presnell, P. Khaenam, V. H. Gersuk, L. Chiche, N. Jourde-Chiche, T. Phillips, G. Klintmalm, A. O'Garra, M. Berry, C. Bloom, R. J. Wilkinson, , D. Chaussabel

The paper develops a targeted transcriptome fingerprinting assay using modular transcriptional repertoires to assess immune functions in clinical settings.

bioRxiv · Mar 24, 2019 · PreprintImmunology