M. Toufiq

High temporal resolution systems profiling reveals distinct patterns of interferon response after Covid-19 mRNA vaccination and SARS-CoV2 infection

This study uses high-temporal-resolution transcriptome profiling to compare interferon responses after mRNA vaccination and SARS-CoV-2 infection, identifying distinct signatures linked to immune outcomes.

A modular framework for the development of targeted Covid-19 blood transcript profiling panels

The paper develops a modular framework for designing targeted blood transcript profiling panels to study the immune response to SARS-CoV-2 infection.

Identification of erythroid cell positive blood transcriptome phenotypes associated with severe respiratory syncytial virus infection

The paper identifies erythroid cell-associated blood transcriptome phenotypes linked to severe RSV infection using meta-analysis of public datasets.

Development and Characterization of a Fixed Repertoire of Blood Transcriptome Modules Based on Co-expression Patterns Across Immunological States

The paper develops a fixed repertoire of blood transcriptome modules based on co-expression patterns across immunological states to provide a stable framework for analyzing and interpreting blood transcriptome data.

A neutrophil-driven inflammatory signature characterizes the blood cell transcriptome fingerprints of Psoriasis and Kawasaki Disease

The paper compares blood transcriptome signatures of psoriasis and Kawasaki Disease, identifying a shared neutrophil-driven inflammatory signature.

Elevation of FAM129A in neutrophils exposed to serum of patients with severe sepsis: in silico investigations during a hands on training workshop and follow on validation of protein expression in neutrophils

The paper investigates FAM129A expression in neutrophils exposed to sepsis serum using transcriptome data and confirms surface expression through bench validation.

A curated collection of transcriptome datasets to investigate the molecular mechanisms of immunoglobulin E-mediated atopic diseases

The paper curates 30 transcriptomic datasets from GEO to study IgE-mediated atopic diseases and provides an online tool for data visualization and metadata annotation.

The abundance of Nudix hydrolase 16 transcripts is elevated in human sepsis: perspectives gained during a hands-on reductionist investigation workshop.

The paper investigates NUDT16 transcript abundance in sepsis using omics data and public datasets, finding elevated levels in septic patients compared to controls.