BiophysicsNature CommunicationsPeer-reviewed
Complex small-world regulatory networks emerge from the 3D organisation of the human genome
C. A. Brackley, N. Gilbert, D. Michieletto…·D. Marenduzzo
This study shows that 3D genome organization leads to complex small-world regulatory networks and stochastic transcription, explaining how GWAS results align with overexpression experiments.
DOI 10.1038/s41467-021-25875-y