Author

M. Nicodemi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:chromatin & epigenetic regulation· 3 Assay:Hi-C· 3 Approach:statistical model· 3 Assay:DNA methylation· 2 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

A. M. Chiariello· 3 shared S. Bianco· 3 shared A. Esposito· 2 shared C. A. Brackley· 2 shared D. Marenduzzo· 2 shared M. Conte· 2 shared A. Abraham· 1 shared A. Fontana· 1 shared

Activity by Year

2016-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersBiophysics

A. M. Chiariello

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4 papers

Recent·Most cited

Multiscale modelling of chromatin 4D organization in SARS-CoV-2 infected cells

A. M. Chiariello, A. Abraham, S. Bianco, A. Esposito, F. Vercellone, M. Conte, A. Fontana, M. Nicodemi

This study uses polymer physics to model how SARS-CoV-2 infection alters chromatin organization and gene regulation in 4D.

bioRxiv · Jul 27, 2023Biophysics

Comparison of the Hi-C, GAM and SPRITE methods by use of polymer models of chromatin

L. Fiorillo, F. Musella, R. Kempfer, A. M. Chiariello, S. Bianco, A. Kukalev, I. Irastorza-Azcarate, A. Esposito, M. Conte, A. Prisco, A. Pombo, M. Nicodemi

The paper compares Hi-C, GAM, and SPRITE methods using polymer models of chromatin to assess their accuracy and performance in capturing 3D genomic structures.

bioRxiv · Apr 24, 2020Biophysics

Complementary chromosome folding by transcription factors and cohesin

M. C. F. Pereira, C. A. Brackley, D. Michieletto, C. Annunziatella, S. Bianco, A. M. Chiariello, M. Nicodemi, D. Marenduzzo

This study combines transcription factor and loop extrusion models to show cohesin acts as a molecular slip-link, not an active motor, in chromosome folding.

bioRxiv · Apr 23, 2018 · PreprintBiophysics

Non-equilibrium chromosome looping via molecular slip-links

C. A. Brackley, J. Johnson, D. Michieletto, A. N. Morozov, M. Nicodemi, P. R. Cook, D. Marenduzzo

This paper introduces a model for chromatin loop formation through diffusive sliding of molecular slip-links, showing it can explain experimental biases without requiring motor activity.

bioRxiv · Dec 21, 2016Biophysics