M. C. Farach-Carson

Development and Characterization of a low intensity vibrational system for microgravity studies

This paper develops and characterizes a low-intensity vibrational bioreactor for microgravity studies on the International Space Station.

Increased deformations are dispensable for cell mechanoresponse in engineered bone analogs mimicking aging bone marrow

This study shows that increased mechanical strain is not necessary for MSC response to vibration in bone marrow analogs, as lower bone volume fractions still showed reduced collagen and F-actin despite higher strains.

Adipose triglyceride lipase is regulated by CAMKK2-AMPK signaling and drives advanced prostate cancer

This study identifies ATGL as a CAMKK2-AMPK target that promotes CRPC progression by enhancing lipase activity and metabolic plasticity, suggesting it as a therapeutic target.

Functionalized Biomimetic Hydrogels Enhance Salivary Stem/Progenitor Cell Organization

This study functionalizes hydrogels to enhance salivary stem/progenitor cell organization and morphogenesis by optimizing crosslink density, integrin-binding sites, and porosity.

SULF1 suppresses Wnt3A-driven growth of bone metastatic prostate cancer in perlecan-modified 3D cancer-stroma-macrophage triculture models

Inflammatory Breast Cancer: a model for investigating cluster-based dissemination

This review discusses molecular mechanisms enabling CTC clusters formation and their higher metastatic potential, using Inflammatory Breast Cancer as an example.