Author

M. Chatzifrangkeskou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D.-E. Pefani· 2 shared E. O'Neill· 2 shared P. A. Skourides· 2 shared A. Koulle· 1 shared A. Panagopoulos· 1 shared D. Karamitros· 1 shared D. Pankova· 1 shared F. Willenbrock· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

D.-E. Pefani

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4 papers

Recent·Most cited

Development of a Xenopus-based assay for high-throughput evaluation of mucociliary flow

I. Antoniades, A. Koulle, M. Chatzifrangkeskou, T. Konstantinou, P. A. Skourides

This paper develops a Xenopus-based assay to evaluate mucociliary flow and screen for therapeutic agents for motile ciliopathies, showing that CBF modulating drugs can improve flow generation.

bioRxiv · Jul 12, 2022 · PreprintCell Biology

The apical Ciliary Adhesion complex is established at the basal foot of motile ciliaand depends on the microtubule network

M. Chatzifrangkeskou, P. A. Skourides

This study identifies the apical Ciliary Adhesion complex as forming at the basal foot of motile cilia and shows its dependence on the microtubule network.

bioRxiv · Jun 28, 2022Cell Biology

53BP1 mediated recruitment of RASSF1A at ribosomal DNA breaks facilitates local ATM signal amplification

S. Tsaridou, G. Velimezi, F. Willenbrock, M. Chatzifrangkeskou, A. Panagopoulos, D. Karamitros, V. G. Gorgoulis, Z. Lygerou, E. O'Neill, D.-E. Pefani

The paper identifies RASSF1A's role in recruiting at rDNA breaks to amplify ATM signals and maintain genome stability, showing its loss leads to DNA damage and reduced cell viability.

bioRxiv · Nov 17, 2021 · PreprintCell Biology

RASSF1A Is Required For The Maintenance Of Nuclear Actin Levels

M. Chatzifrangkeskou, D.-E. Pefani, M. Eyres, I. Vendrell, R. Fischer, D. Pankova, E. O'Neill

This study identifies RASSF1A as a regulator of nuclear actin levels by supporting exportin-6 binding to RAN GTPase, linking it to tumor suppression through MRTF/SRF regulation.

bioRxiv · Feb 24, 2019Cell Biology