Author

Z. Lygerou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Georgakilas· 1 shared A. Kotsinas· 1 shared A. Panagopoulos· 1 shared A. Polyzos· 1 shared C. Glytsou· 1 shared C. Lukas· 1 shared C. S. Sorensen· 1 shared D. Karamitros· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Georgakilas

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Author profile →

2 papers

Recent·Most cited

53BP1 mediated recruitment of RASSF1A at ribosomal DNA breaks facilitates local ATM signal amplification

S. Tsaridou, G. Velimezi, F. Willenbrock, M. Chatzifrangkeskou, A. Panagopoulos, D. Karamitros, V. G. Gorgoulis, Z. Lygerou, E. O'Neill, D.-E. Pefani

The paper identifies RASSF1A's role in recruiting at rDNA breaks to amplify ATM signals and maintain genome stability, showing its loss leads to DNA damage and reduced cell viability.

bioRxiv · Nov 17, 2021 · PreprintCell Biology

Mutational signatures reveal the role of RAD52 in p53-independent p21 driven genomic instability

P. Galanos, G. Pappas, A. Polyzos, A. Kotsinas, I. Svolaki, N. Giakoumakis, C. Glytsou, I. Pateras, U. Swain, V. Souliotis, A. Georgakilas, N. Geacintov, L. Scorrano, C. Lukas, J. Lukas, , V. Gorgoulis

This study shows chronic p21WAF1/Cip1 expression causes genomic instability by suppressing DNA repair pathways, revealing Rad52 as a key player in this process.

bioRxiv · Sep 28, 2017Cancer Biology