CLEC-2 promotes inflammatory peritoneal macrophage emigration to draining lymph nodes during endotoxemia
J. H. Bourne, N. Beristain Covarrubias, M. zuidscherwoude, J. Campos, Y. Di, E. Garlick, M. Colicchia, L. V. Terry, S. G. Thomas, A. Brill, J. Barry, S. P. Watson, J. Rayes
This study identifies that recombinant CLEC-2-Fc promotes the emigration of inflammatory peritoneal macrophages to draining lymph nodes, reducing local inflammation during endotoxemia.
bioRxiv · Dec 21, 2020 · PreprintImmunology