Author

S. P. Watson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

S. G. Thomas· 3 shared J. Rayes· 2 shared Y. Di· 2 shared A. Alshayea· 1 shared A. Brill· 1 shared A. Carestia· 1 shared A. F. Cunningham· 1 shared A. L. Dalby· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersPhysiology

S. G. Thomas

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Discrete and conserved inflammatory signatures drive thrombosis in different organs after Salmonella infection

M. Perez-Toledo, N. Beristain-Covarrubias, J. Pillaye, R. R. Persaud, E. Marcial-Juarez, S. E. Jossi, J. R. Hitchcock, A. Alshayea, W. M. Channell, R. E. Lamerton, D. P. Kavanagh, A. Carestia, W. G. Horsnell, I. R. Henderson, N. Mackman, , A. F. Cunningham

This study identifies discrete inflammatory signatures driving thrombosis in the spleen and liver after Salmonella infection, revealing both organ-specific and shared mechanisms.

bioRxiv · Jan 16, 2024 · PreprintImmunology

Antibody-mediated depletion of human CLEC-2 in a novel humanised mouse model

H. C. Brown, S. Beck, S. Navarro, Y. Di, E. M. Soriano Jerez, J. Kaczmarzyk, S. G. Thomas, V. Mirakaj, S. P. Watson, B. Nieswandt, D. Stegner

This paper develops a humanised CLEC-2 mouse model and a monoclonal antibody to test anti-CLEC-2 therapeutics, showing transient thrombocytopenia without affecting haemostasis.

bioRxiv · Oct 3, 2021 · PreprintPhysiology

Analysis of Preplatelets and Their Barbell Platelet Derivatives by Imaging Flow Cytometry

S. Kemble, A. L. Dalby, G. C. Lowe, P. L. Nicolson, S. P. Watson, Y. A. Senis, S. G. Thomas, P. Harrison

This study uses imaging flow cytometry and microscopy to show that preplatelets and barbell platelets are immature structures that transform into mature platelets in mice and humans.

bioRxiv · Jul 30, 2021Cell Biology

CLEC-2 promotes inflammatory peritoneal macrophage emigration to draining lymph nodes during endotoxemia

J. H. Bourne, N. Beristain Covarrubias, M. zuidscherwoude, J. Campos, Y. Di, E. Garlick, M. Colicchia, L. V. Terry, S. G. Thomas, A. Brill, J. Barry, S. P. Watson, J. Rayes

This study identifies that recombinant CLEC-2-Fc promotes the emigration of inflammatory peritoneal macrophages to draining lymph nodes, reducing local inflammation during endotoxemia.

bioRxiv · Dec 21, 2020 · PreprintImmunology

Immobilised collagen prevents shedding and induces sustained GPVI clustering and signalling in platelets.

C. Pallini, J. A. Pike, C. O'Shea, R. K. Andrews, E. E. Gardiner, S. P. Watson, N. S. Poulter

This study shows immobilized collagen prevents GPVI shedding and sustains its clustering and signaling in platelets for at least 3 hours.

bioRxiv · Jul 7, 2020 · PreprintCell Biology