BRAFV600E induces reversible mitotic arrest in human melanocytes via microRNA-mediated suppression of AURKB.
A. S. McNeal, R. L. Belote, H. Zeng, M. Urquijo, K. Barker, R. Torres, M. Curtin, A. H. Shain, R. H. Andtbacka, S. L. Holmen, D. H. Lum, T. McCalmont, M. W. VanBrocklin, D. Grossman, M. L. Wei, , R. L. Judson-Torres
This study identifies microRNA-mediated suppression of AURKB as a mechanism by which BRAFV600E induces reversible mitotic arrest in human melanocytes, contributing to nevus formation.
bioRxiv · May 21, 2020Cancer Biology