Author

K. Barker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Bellini· 1 shared A. Carcaboso· 1 shared A. Goodman· 1 shared A. H. Shain· 1 shared A. S. McNeal· 1 shared A. Saint-Charles· 1 shared B. Geoerger· 1 shared B. Martins da Costa· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Bellini

Mutual co-authors in cluster

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3 papers

Recent·Most cited

COMBINATION THERAPIES TARGETING ALK-ABERRANT NEUROBLASTOMA IN PRECLINICAL MODELS.

E. Tucker, I. Jimenez, L. Chen, A. Bellini, C. Gorrini, E. Calton, Q. Gao, H. Che, E. Poon, Y. Jamin, B. Martins da Costa, K. Barker, S. Shrestha, C. Hutchinson, S. Dhariwal, , G. Schleiermacher

This study evaluates lorlatinib, an ALK inhibitor, in combination with chemotherapy or idasanutlin in preclinical neuroblastoma models, finding synergy in models with high ALK expression.

Clinical Cancer Research · Apr 3, 2023Peer-reviewedCancer Biology

BRAFV600E induces reversible mitotic arrest in human melanocytes via microRNA-mediated suppression of AURKB.

A. S. McNeal, R. L. Belote, H. Zeng, M. Urquijo, K. Barker, R. Torres, M. Curtin, A. H. Shain, R. H. Andtbacka, S. L. Holmen, D. H. Lum, T. McCalmont, M. W. VanBrocklin, D. Grossman, M. L. Wei, , R. L. Judson-Torres

This study identifies microRNA-mediated suppression of AURKB as a mechanism by which BRAFV600E induces reversible mitotic arrest in human melanocytes, contributing to nevus formation.

bioRxiv · May 21, 2020Cancer Biology

High multiplex, digital spatial profiling of proteins and RNA in fixed tissue using genomic detection methods

C. R. Merritt, G. T. Ong, S. Church, K. Barker, G. Geiss, M. Hoang, J. Jung, Y. Liang, J. McKay-Fleisch, K. Nguyen, K. Sorg, I. Sprague, C. Warren, S. Warren, Z. Zhou, , J. M. Beechem

This paper introduces Digital Spatial Profiling (DSP), a method for high-plex spatial analysis of proteins and RNA in tissue, and demonstrates its application in studying immune and cancer microenvironments.

bioRxiv · Feb 26, 2019 · PreprintPathology