T Cell Calcium Dynamics Visualized in a Ratiometric tdTomato-GCaMP6f Transgenic Reporter Mouse
T. X. Dong, S. Othy, A. Jairaman, J. Skupsky, A. Zavala, I. Parker, J. L. Dynes, M. D. Cahalan
The paper develops a transgenic Ca2+ reporter mouse to visualize T cell calcium dynamics in vivo and demonstrates localized Ca2+ signaling during migration and receptor engagement.
bioRxiv · Oct 18, 2017Cell Biology