Author

T. X. Dong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:imaging· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Jairaman· 2 shared I. Parker· 2 shared J. L. Dynes· 2 shared S. Othy· 2 shared A. Zavala· 1 shared B. Tang· 1 shared C. Akunwafo· 1 shared H. Dong· 1 shared

Activity by Year

2017-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

A. Jairaman

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

VPAC1 couples with TRPV4 channel to promote calcium-dependent gastric cancer progression

B. Tang, J. Wu, M. X. Zhu, X. Sun, J. Liu, R. Xie, T. X. Dong, Y. Xiao, J. M. Carethers, S.-M. Yang, H. Dong

This study shows that VPAC1 and TRPV4 channel interaction promotes calcium-dependent gastric cancer progression through a positive feedback loop involving VIP secretion.

bioRxiv · Jul 2, 2018Cancer Biology

T Cell Calcium Dynamics Visualized in a Ratiometric tdTomato-GCaMP6f Transgenic Reporter Mouse

T. X. Dong, S. Othy, A. Jairaman, J. Skupsky, A. Zavala, I. Parker, J. L. Dynes, M. D. Cahalan

The paper develops a transgenic Ca2+ reporter mouse to visualize T cell calcium dynamics in vivo and demonstrates localized Ca2+ signaling during migration and receptor engagement.

bioRxiv · Oct 18, 2017Cell Biology

Intermittent Ca2+ signals mediated by Orai1 regulate basal T cell motility

T. X. Dong, S. Othy, M. L. Greenberg, A. Jairaman, C. Akunwafo, S. Leverrier, Y. Yu, I. Parker, J. L. Dynes, Michael D. Cahalan

This study shows that Orai1-mediated Ca2+ signals regulate basal T cell motility by reducing pauses during migration, enhancing cell velocity in confined spaces.

bioRxiv · Apr 19, 2017Immunology