Author

M. D. Hein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. Y. Kupke· 2 shared U. Reichl· 2 shared A. Chawla· 1 shared D. Bruder· 1 shared H. Shkarlet· 1 shared L. Cicin-Sain· 1 shared M. Cattaneo· 1 shared P. Marichal-Gallardo· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioengineering

S. Y. Kupke

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2 papers

Recent·Most cited

Cell culture-based production of defective interfering influenza A virus particles in perfusion mode using an alternating tangential flow filtration system

M. D. Hein, A. Chawla, M. Cattaneo, S. Y. Kupke, Y. Genzel, U. Reichl

This paper establishes an automated perfusion process for producing IAV DIPs using an alternating tangential flow filtration system, achieving high DIP titers and enabling continuous virus harvesting.

bioRxiv · Jun 7, 2021Bioengineering

Antiviral activity of influenza A virus defective interfering particles against SARS-CoV-2 replication in vitro through stimulation of innate immunity

U. Rand, S. Y. Kupke, H. Shkarlet, M. D. Hein, T. Hirsch, P. Marichal-Gallardo, L. Cicin-Sain, U. Reichl, D. Bruder

This study shows that influenza A virus defective interfering particles inhibit SARS-CoV-2 replication in vitro by enhancing innate immunity through JAK/STAT signaling.

bioRxiv · Feb 19, 2021Microbiology