Author

M. D. L. Johnson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

S. V. Menghani· 2 shared Y. Sanchez-Rosario· 2 shared C. Pok· 1 shared D. Reinartz· 1 shared F. Gao· 1 shared H. L. O'Brien· 1 shared H. Y. O'Brien· 1 shared J. E. Wilson· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

S. V. Menghani

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Author profile →

4 papers

Recent·Most cited

Iron promotes copper entry in Streptococcus pneumoniae

Y. Sanchez-Rosario, M. D. L. Johnson

The paper shows that iron promotes copper entry in Streptococcus pneumoniae through iron transport systems, with copper association decreasing in iron transport knockouts.

bioRxiv · Dec 17, 2023 · PreprintMicrobiology

Oral Streptococci S. anginosus and S. mitis induce distinct morphological, inflammatory, and metabolic signatures in macrophages

M. D. L. Johnson, S. Senthilkumar, V. Gunda, D. Reinartz, K. Pond, P. V. Santiago Raj, J. E. Wilson

This study compares the effects of S. anginosus and S. mitis on macrophage inflammation and metabolism, finding S. anginosus induces stronger proinflammatory responses and unique metabolic changes.

bioRxiv · Aug 28, 2023 · PreprintMicrobiology

Compounds derived from N,N-dimethyldithiocarbamate are effective copper-dependent antimicrobials against Streptococcus pneumoniae

M. D. L. Johnson, S. V. Menghani, Y. Sanchez-Rosario, C. Pok, R. Liu, F. Gao, H. L. O'Brien, M. Neubert, K. Ochoa, R. D. Hellinger, W. Wang

The paper develops and tests novel DMDC-derived compounds as copper-dependent antimicrobials against Streptococcus pneumoniae, showing effectiveness in vitro and in vivo.

bioRxiv · Sep 23, 2022 · PreprintMicrobiology

Characterization of consensus operator site for Streptococcus pneumoniae copper repressor, CopY

H. Y. O'Brien, J. W. Alvin, S. V. Menghani, K. Van Doorslaer, M. D. L. Johnson

This study identifies a more comprehensive consensus operator sequence for the copper repressor CopY in Streptococcus pneumoniae through bioinformatics and experimental validation.

bioRxiv · Jun 21, 2019 · PreprintMicrobiology