Author

M. D. Milsom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. B. Lipka· 2 shared J.-P. Mallm· 2 shared R. Bogeska· 2 shared S. Haas· 2 shared S. Staeble· 2 shared A. Ertl· 1 shared A. Petri· 1 shared A.-H. Maag· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

D. B. Lipka

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Oncogenic RAS-Pathway Activation Drives Oncofetal Reprogramming and Creates Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia

M. Hartmann, M. Schoenung, J. Rajak, V. Maurer, L. Hai, K. Bauer, M. Hakobyan, S. Staeble, J. Langstein, L. Jardine, R. Roelz, S. Bohler, E. Khabirova, A.-H. Maag, D. Vonficht, , D. B. Lipka

This study identifies oncofetal reprogramming in juvenile myelomonocytic leukemia, linking RAS-pathway activation to fetal gene expression and revealing CD52 as a therapeutic target.

bioRxiv · Oct 27, 2023Cancer Biology

IRON REGULATORY PROTEIN (IRP)-MEDIATED IRON HOMEOSTASIS IS CRITICAL FOR NEUTROPHIL DEVELOPMENT AND DIFFERENTIATION IN THE BONE MARROW

M. Bonadonna, S. Altamura, E. Tybl, G. Palais, M. Qatato, M. Polycarpou-Schwarz, M. Schneider, C. Kalk, W. Ruediger, A. Ertl, N. Anstee, R. Bogeska, D. Helm, M. D. Milsom, B. Galy

This study shows that IRP-mediated iron homeostasis is essential for neutrophil development and differentiation in the bone marrow, with no effect on monocyte counts.

bioRxiv · Mar 16, 2022Immunology

Hematopoietic stem cells fail to regenerate following inflammatory challenge.

R. Bogeska, P. Kaschutnig, M. Fawaz, A.-M. Mikecin, M. Buechler-Schaeff, S. Paffenholz, N. Asada, F. Frauhammer, F. Buettner, M. Ball, J. Knoch, S. Staeble, D. Walter, A. Petri, M. J. Carreno-Gonzalez, , M. D. Milsom

This study shows that repeated inflammatory challenges lead to progressive depletion of functional HSCs with no recovery, contributing to age-related hematopoietic decline.

bioRxiv · Aug 1, 2020Cell Biology