M. de Souza Santos

This study identifies VPA0226, a lipase secreted by Vibrio parahaemolyticus, which esterifies cholesterol with host fatty acids to weaken the plasma membrane and enable bacterial egress from host cells.

This study determines high-resolution cryo-EM structures of E. coli hemolysin ClyA oligomers, revealing new oligomeric states and mechanistic insights into pore assembly.

This study shows that VopL, a T3SS2 effector of Vibrio parahaemolyticus, inhibits host ROS production by disrupting actin cytoskeleton function, thereby promoting bacterial intracellular survival.