Author

M. Diebold

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

B. Adhikari· 2 shared C. Sotriffer· 2 shared E. Wolf· 2 shared A. Cagol· 1 shared A. Doelle· 1 shared A. Junker· 1 shared A. Kraemer· 1 shared A. Mathias· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

B. Adhikari

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Identification of Suitable Target/E3 Ligase Pairs for PROTAC Development using a Rapamycin-induced Proximity Assay (RiPA)

B. Adhikari, K. Schneider, M. Diebold, C. Sotriffer, E. Wolf

This paper introduces a rapamycin-induced proximity assay (RiPA) to identify effective E3 ligase-target pairs for PROTAC development, demonstrating its ability to predict degradation capabilities.

eLife · Dec 6, 2024Peer-reviewedBiochemistry

Cell-binding IgM in CSF is distinctive of multiple sclerosis and targets the iron transporter SCARA5

I. Callegari, J. Oechtering, M. Schneider, S. Perriot, A. Mathias, M. Voortman, A. Cagol, U. Lanner, M. Diebold, S. Holdermann, V. Kreiner, B. Becher, C. Granziera, A. Junker, R. Du Pasquier, , T. Derfuss

The paper identifies cell-binding IgM in CSF that targets SCARA5 in multiple sclerosis, linking it to complement activation and T cell infiltration.

bioRxiv · Sep 29, 2023Immunology

Design, Synthesis and Evaluation of WD-repeat containing protein 5 (WDR5) degraders

A. Doelle, B. Adhikari, A. Kraemer, J. Weckesser, N. Berner, L.-M. Berger, M. Diebold, M. Szewczyk, D. Barsyte-Lovejoy, C. Arrowsmith, J. Gerbel, F. Loehr, V. Doetsch, M. Eilers, S. Heinzlmeir, , S. Knapp

This study designs, synthesizes, and evaluates two series of WDR5 degraders, showing that linker length and nature affect degradation efficacy.

bioRxiv · Apr 12, 2021 · PreprintCancer Biology