Cancer BiologybioRxivPreprint
Design, Synthesis and Evaluation of WD-repeat containing protein 5 (WDR5) degraders
A. Doelle, B. Adhikari, A. Kraemer…·S. Knapp
This study designs, synthesizes, and evaluates two series of WDR5 degraders, showing that linker length and nature affect degradation efficacy.
DOI 10.1101/2021.04.12.439490