Co-chaperone involvement in knob biogenesis implicates host-derived chaperones in malaria virulence
M. Diehl, S. Weber, M. Cyrklaff, C. P. Sanchez, C. A. Beretta, L. Roling, C. S. Simon, J. Guizetti, M. P. Mayer, J. M. Przyborski
This study shows that the malaria parasite protein PFA66, a J-domain protein, works with host-derived HSP70 to facilitate knob biogenesis and cytoadherence in infected erythrocytes.
bioRxiv · Mar 11, 2021Cell Biology