O-GlcNAc transferase suppresses necroptosis and liver fibrosis
B. Zhang, M.-D. Li, R. Yin, Y. Liu, Y. Yang, K. A. Mitchell-Richards, J. H. Nam, R. Li, L. Wang, Y. Iwakiri, D. Chung, M. E. Robert, B. E. Ehrlich, A. M. Bennett, J. Yu, , X. Yang
This study identifies O-GlcNAc transferase as a suppressor of hepatocyte necroptosis and liver fibrosis, using both human and mouse models.
bioRxiv · Jan 14, 2019Physiology