Author

B. E. Ehrlich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 3 Approach:biophysical modeling· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

E. Kruglov· 2 shared M. F. Leite· 2 shared M. Nathanson· 2 shared N. Ogino· 2 shared A. Cabral· 1 shared A. M. Bennett· 1 shared B. Zhang· 1 shared D. A. Hafler· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

E. Kruglov

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Adaptation to volumetric compression drives hepatoblastoma cells to an apoptosis-resistant and invasive phenotype

X. Gong, N. Ogino, M. F. Leite, Z. Chen, R. Liu, E. Kruglov, K. Flores, A. Cabral, G. M. M. Mendes, B. E. Ehrlich, M. Mak

This study shows that volumetric compression in liver cancer cells leads to transcriptional reprogramming, increased invasiveness, and chemoresistance, with potential reversal via calcium signaling.

bioRxiv · Oct 8, 2023 · PreprintCancer Biology

Neutrophils regulate ITPR2 levels in epithelia by direct injection of elastase

N. Ogino, M. F. Leite, E. Kruglov, H. Asashima, D. A. Hafler, B. E. Ehrlich, M. Nathanson

The paper shows neutrophils inject elastase into hepatocytes, reducing ITPR2 levels and calcium signals without damaging cells, and identifies a compensatory response in liver biopsies.

bioRxiv · Sep 13, 2022 · PreprintCell Biology

O-GlcNAc transferase suppresses necroptosis and liver fibrosis

B. Zhang, M.-D. Li, R. Yin, Y. Liu, Y. Yang, K. A. Mitchell-Richards, J. H. Nam, R. Li, L. Wang, Y. Iwakiri, D. Chung, M. E. Robert, B. E. Ehrlich, A. M. Bennett, J. Yu, , X. Yang

This study identifies O-GlcNAc transferase as a suppressor of hepatocyte necroptosis and liver fibrosis, using both human and mouse models.

bioRxiv · Jan 14, 2019Physiology