Author

M. E. van Breugel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

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Research Focus:chromatin & epigenetic regulation· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. Crocker· 2 shared T. Fuqua· 2 shared A. Halavatyi· 1 shared A. Tsai· 1 shared C. Tischer· 1 shared D. L. Stern· 1 shared J. Jordan· 1 shared N. Abe· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersEvolutionary Biology

J. Crocker

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2 papers

Recent·Most cited

Mutational scans reveal differential evolvability of Drosophila promoters and enhancers

X. C. Li, T. Fuqua, M. E. van Breugel, J. Crocker

The paper investigates the evolvability of Drosophila promoters and enhancers by analyzing mutation effects on gene expression patterns.

bioRxiv · Oct 17, 2022 · PreprintEvolutionary Biology

Dense encoding of developmental regulatory information may constrain evolvability

T. Fuqua, J. Jordan, M. E. van Breugel, A. Halavatyi, C. Tischer, P. Polidoro, N. Abe, A. Tsai, R. S. Mann, D. L. Stern, J. Crocker

The paper investigates the evolutionary potential of regulatory changes in developmental enhancers by analyzing mutations in Drosophila melanogaster, finding that most mutations affect gene expression and suggest dense regulatory information that may constrain evolvability.

bioRxiv · Apr 17, 2020 · PreprintEvolutionary Biology