T. Fuqua

The emergence and evolution of gene expression in genome regions replete with regulatory motifs

This study investigates how promoter motifs influence promoter emergence and evolution by mutagenizing promoter islands and measuring gene expression in mutants.

The latent cis-regulatory potential of mobile DNA

This study shows that transposable elements in E. coli can evolve de-novo promoter activity through mutations, highlighting their latent cis-regulatory potential.

Mutational scans reveal differential evolvability of Drosophila promoters and enhancers

The paper investigates the evolvability of Drosophila promoters and enhancers by analyzing mutation effects on gene expression patterns.

Dense encoding of developmental regulatory information may constrain evolvability

The paper investigates the evolutionary potential of regulatory changes in developmental enhancers by analyzing mutations in Drosophila melanogaster, finding that most mutations affect gene expression and suggest dense regulatory information that may constrain evolvability.