Author

P. Polidoro

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Evolutionary Biology· 1

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Research Focus:chromatin & epigenetic regulation· 1 Organism:Drosophila· 1 Approach:experimental assay· 1

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A. Halavatyi· 1 shared A. Tsai· 1 shared C. Tischer· 1 shared D. L. Stern· 1 shared J. Crocker· 1 shared J. Jordan· 1 shared M. E. van Breugel· 1 shared N. Abe· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperEvolutionary Biology

A. Halavatyi

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1 paper

Recent·Most cited

Dense encoding of developmental regulatory information may constrain evolvability

T. Fuqua, J. Jordan, M. E. van Breugel, A. Halavatyi, C. Tischer, P. Polidoro, N. Abe, A. Tsai, R. S. Mann, D. L. Stern, J. Crocker

The paper investigates the evolutionary potential of regulatory changes in developmental enhancers by analyzing mutations in Drosophila melanogaster, finding that most mutations affect gene expression and suggest dense regulatory information that may constrain evolvability.

bioRxiv · Apr 17, 2020 · PreprintEvolutionary Biology