Author

R. S. Mann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

A. Halavatyi· 1 shared A. P. Sergeeva· 1 shared A. Tsai· 1 shared B. Bornstein· 1 shared B. Honig· 1 shared C. Tischer· 1 shared D. L. Stern· 1 shared D. S. Lopez· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperEvolutionary Biology

A. Halavatyi

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2 papers

Recent·Most cited

Cis inhibition of co-expressed DIPs and Dprs shapes neural development

N. C. Morano, D. S. Lopez, H. Meltzer, A. P. Sergeeva, P. S. Katsamba, K. D. Rostam, H. P. Gupta, J. E. Becker, B. Bornstein, F. Cosmanescu, O. Schuldiner, B. Honig, R. S. Mann, L. Shapiro

The paper shows that DIPs and Dprs interact in cis within the same cells, regulating trans interactions and influencing neural development in Drosophila.

PLOS Biology · Mar 3, 2025Peer-reviewedBiochemistry

Dense encoding of developmental regulatory information may constrain evolvability

T. Fuqua, J. Jordan, M. E. van Breugel, A. Halavatyi, C. Tischer, P. Polidoro, N. Abe, A. Tsai, R. S. Mann, D. L. Stern, J. Crocker

The paper investigates the evolutionary potential of regulatory changes in developmental enhancers by analyzing mutations in Drosophila melanogaster, finding that most mutations affect gene expression and suggest dense regulatory information that may constrain evolvability.

bioRxiv · Apr 17, 2020 · PreprintEvolutionary Biology