Neuronal Hyperexcitability is a DLK-dependent Trigger of HSV-1 Reactivation that can be Induced by IL-1
S. R. Cuddy, A. R. Schinlever, S. Dochnal, J. B. Suzich, P. Kundu, T. K. Downs, M. Farah, B. Desai, C. Boutell, A. R. Cliffe
This study shows that neuronal hyperexcitability, induced by IL-1β, triggers HSV-1 reactivation through DLK/JNK pathway and histone phosphorylation.
bioRxiv · Apr 16, 2020 · PreprintMicrobiology