M. G. Jackson

Characterisation of behaviours relevant to apathy syndrome in the aged male rat

This study investigates whether aged rats exhibit behavioural deficits relevant to apathy syndrome across multiple domains, finding deficits in cognitive flexibility but not other domains, suggesting aged rats are not a suitable model for age-related apathy.

Validation of a non-appetitive effort-based foraging task as a measure of motivational state in male mice

This paper validates a non-appetitive effort-based foraging task in mice as a measure of motivational state, showing sensitivity to dopaminergic modulation and phenotypic models of motivational deficits.

Evidence for an apathy phenotype in aged mice

This study identifies behavioral and physiological changes in aged mice that suggest an apathy phenotype, including reduced reward sensitivity and stress reactivity.