Author

S. L. Lightman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 2 Physiology· 2

Signature Assays, Organisms & Methods

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Assay:behavioral assay· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

E. S. J. Robinson· 2 shared M. G. Jackson· 2 shared B. Gibbison· 1 shared C. A. Rogers· 1 shared D. Galvis· 1 shared E. Zavala· 1 shared G. D. Angelini· 1 shared G. Gilmour· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersAnimal Behavior & Cognition

E. S. J. Robinson

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Author profile →

4 papers

Recent·Most cited

Characterisation of behaviours relevant to apathy syndrome in the aged male rat

M. G. Jackson, S. L. Lightman, E. S. J. Robinson

This study investigates whether aged rats exhibit behavioural deficits relevant to apathy syndrome across multiple domains, finding deficits in cognitive flexibility but not other domains, suggesting aged rats are not a suitable model for age-related apathy.

bioRxiv · Feb 2, 2024Animal Behavior & Cognition

The dynamic interaction of systemic inflammation and the hypothalamic-pituitary-adrenal (HPA) axis during and after major surgery

D. Galvis, E. Zavala, J. J. Walker, T. Upton, S. L. Lightman, G. D. Angelini, J. Evans, C. A. Rogers, K. Phillips, B. Gibbison

This study examines how systemic inflammation and the HPA axis respond during and after major surgery, identifying three cortisol response phenotypes and their clinical implications.

bioRxiv · Aug 16, 2021Physiology

Evidence for an apathy phenotype in aged mice

M. G. Jackson, S. L. Lightman, G. Gilmour, H. Marston, E. S. J. Robinson

This study identifies behavioral and physiological changes in aged mice that suggest an apathy phenotype, including reduced reward sensitivity and stress reactivity.

bioRxiv · May 28, 2020 · PreprintAnimal Behavior & Cognition

Mathematical modelling elucidates core mechanisms underpinning GnRH pulse generation

M. Voliotis, X.-F. Li, R. De Burgh, G. Lass, S. L. Lightman, K. T. O'Byrne, K. Tsaneva-Atanasova

The paper develops a mathematical model of the GnRH pulse generator, showing that increasing basal activity leads to pulsatile luteinizing hormone release and frequency changes through feedback mechanisms.

bioRxiv · Dec 11, 2018 · PreprintPhysiology