The mechanoreceptor PIEZO1 is a novel oncogene in glioma by promoting astrocyte reactivity
P. Blanco-Carlon, M. A. Navarro-Aguadero, P. Aguilar-Garrido, A. Otero-Sobrino, M. Hernandez-Sanchez, A. Arroyo-Barea, O. Grana-Castro, R. Gargini, R. M. Garcia-Martin, A. Hernandez-Lain, M. Perez-Martinez, J. Gomez-Alonso, S. Ortega, J. Martinez-Lopez, M. Gallardo, M. Velasco-Estevez
This study identifies PIEZO1 as an oncogene in glioma that promotes astrocyte reactivity and is associated with worse prognosis in male patients.
bioRxiv · Apr 30, 2024 · PreprintCancer Biology