Ubiquinone biosynthesis over the entire O2 range: characterization of a conserved, O2-independent pathway
L. Pelosi, C.-D.-T. Vo, S. Abby, L. Loiseau, B. Rascalou, M. Hajj Chehade, B. Faivre, M. Gousse, C. Chenal, N. Touati, L. Binet, D. Cornu, C. D. Fyfe, M. Fontecave, F. Barras, , F. Pierrel
The paper identifies an O2-independent ubiquinone biosynthesis pathway in bacteria, showing its presence in human pathogens and its role in metabolic flexibility across O2 gradients.
bioRxiv · Jun 12, 2019Microbiology