Author

F. Barras

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:E. coli· 4 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Organism:bacteria (other)· 2 Approach:biophysical modeling· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

F. Pierrel· 4 shared L. Pelosi· 4 shared B. Faivre· 2 shared C.-D.-T. Vo· 2 shared E. Bouveret· 2 shared J. El Khoury· 2 shared L. Loiseau· 2 shared M. Fontecave· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersMicrobiology

F. Pierrel

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Role of the Escherichia coli ubiquinone-synthesizing UbiUVT pathway in adaptation to changing respiratory conditions

R. Arias-Cartin, K. Kazemzadeh Ferizhendi, E. Sechet, L. Pelosi, C. Loeuillet, F. Pierrel, F. Barras, E. Bouveret

This paper investigates the role of the UbiUV-dependent ubiquinone biosynthesis pathway in E. coli adaptation to changing oxygen conditions and identifies its importance in anaerobic respiration and uracil biosynthesis.

bioRxiv · Mar 15, 2023 · PreprintMicrobiology

A multidisciplinary analysis of the as-isolated Escherichia coli SufBC2D complex reveals the presence of two new iron-sulfur clusters

G. Veronesi, J. Perard, M. Clemancey, C. Gerez, Y. Duverger, I. Kieffer, F. Barras, S. Gambarelli, G. Blondin, s. ollagnier de choudens

The paper characterizes the native Fe-S clusters in the SufBC2D complex from E. coli using spectroscopy and biochemistry, identifying two new clusters.

bioRxiv · Mar 29, 2022 · PreprintBiochemistry

The AAA+ ATPase RavA and its binding partner ViaA modulate E. coli aminoglycoside sensitivity through interaction with the inner membrane

J. Felix, L. Bumba, C. Liesche, A. Fraudeau, F. Rebeille, J. El Khoury, K. Huard, B. Gallet, C. Moriscot, J.-P. Kleman, Y. Duhoo, M. Jessop, E. Kandiah, F. Barras, J. Jouhet, I. Gutsche

This study identifies RavA and ViaA as modulators of E. coli aminoglycoside sensitivity through lipid interactions affecting membrane morphology and antibiotic resistance.

bioRxiv · Feb 6, 2022Microbiology

The AAA+ ATPase RavA-ViaA complex sensitizes Escherichia coli to aminoglycosides under anaerobic low energy conservation conditions

J. El Khoury, J. Zamarreno, A. Huguenot, B. Py, F. Barras

The paper shows that the RavA-ViaA complex in E. coli increases sensitivity to aminoglycosides under anaerobic low energy conditions by enhancing uptake.

bioRxiv · Jan 13, 2022 · PreprintMicrobiology

The biosynthetic pathway of ubiquinone contributes to pathogenicity of Francisella

K. Kazemzadeh, M. Hajj Chehade, H. Gautier, B. Camille, Y. Caspar, L. Loiseau, F. Barras, F. Pierrel, L. Pelosi

This study identifies the ubiquinone biosynthetic pathway in Francisella novicida, showing UQ8 as the major quinone and demonstrating its essential role in growth and pathogenicity.

bioRxiv · Aug 3, 2021Microbiology

The O2-independent pathway of ubiquinone biosynthesis is essential for denitrification in Pseudomonas aeruginosa

C.-D.-T. Vo, J. Michaud, S. Elsen, B. Faivre, E. Bouveret, F. Barras, M. Fontecave, F. Pierrel, M. Lombard, L. Pelosi

bioRxiv · Mar 22, 2020Biochemistry

Ubiquinone biosynthesis over the entire O2 range: characterization of a conserved, O2-independent pathway

L. Pelosi, C.-D.-T. Vo, S. Abby, L. Loiseau, B. Rascalou, M. Hajj Chehade, B. Faivre, M. Gousse, C. Chenal, N. Touati, L. Binet, D. Cornu, C. D. Fyfe, M. Fontecave, F. Barras, , F. Pierrel

The paper identifies an O2-independent ubiquinone biosynthesis pathway in bacteria, showing its presence in human pathogens and its role in metabolic flexibility across O2 gradients.

bioRxiv · Jun 12, 2019Microbiology