M. Grant

The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes

This study shows that USP9X stabilizes RIT1 protein and that its depletion reduces RIT1 abundance and sensitizes cells to EGFR inhibitors.

Rapid local and systemic jasmonate signalling drives initiation and establishment of plant systemic immunity

The paper shows that jasmonate signaling is essential for initiating and establishing systemic immunity in plants through local and rapid systemic responses.

Plant and prokaryotic TIR domains generate distinct cyclic ADPR NADase products

This study investigates whether prokaryotic Thoeris TIRs can cross-activate plant TIR-immunity and finds they generate overlapping cADPR isomers but have distinct signaling requirements.

Chemical structures of cyclic ADP ribose (cADPR) isomers and the molecular basis of their production and signaling

The paper reports the chemical structures of two cADPR isomers, their production mechanism, and their roles in antiviral signaling and plant immunity suppression.

Proteogenomic Discovery of Neoantigens Facilitates Personalized Multi-antigen Targeted T cell Immunotherapy for Brain Tumors

This study identifies tumor-specific peptides in pediatric brain tumors using proteogenomics to enable personalized T cell immunotherapy.

The plant endoplasmic reticulum is both receptive and responsive to pathogen effectors

The paper shows that plant ER morphology changes rapidly during infection and identifies ER-localized effectors that may suppress immunity.

Evaluation of 20 enset (Ensete ventricosum) landraces for response to Xanthomonas vasicola pv. musacearum infection

This study evaluates 20 enset landraces for their response to Xanthomonas vasicola pv. musacearum infection, identifying three with the lowest susceptibility.

Transfer of Xanthomonas campestris pv. arecae, and Xanthomonas campestris pv. musacearum to Xanthomonas vasicola (Vauterin) as Xanthomonas vasicola pv. arecae comb. nov., and Xanthomonas vasicola pv. musacearum comb. nov. and description of Xanthomonas vasicola pv. vasculorum pv. nov.

The paper transfers two Xanthomonas species to Xanthomonas vasicola and describes a new pathovar.