Efficient and robust NK-Cell transduction with Baboon Envelope pseudotyped lentivector: a major tool for immunotherapy
A. B. L. Colamartino, W. Lemieux, P. Bifsha, S. Nicoletti, N. Chakravarti, J. S. Remon, H. Romero, S. Selleri, K. Beland, M. Guiot, C. Tremblay-Laganiere, R. Dicaire, L. Barreiro, D. A. Lee, E. Verhoeyen, E. Haddad
This paper demonstrates that Baboon Envelope pseudotyped lentiviral vectors efficiently transduce NK-cells, enabling CAR expression and specific killing of cancer cell lines.
bioRxiv · May 2, 2019Immunology