Towards Modular Engineering of Cell Signalling: Topographically-Textured Microparticles Induce Osteogenesis via Activation of Canonical Hedgehog Signalling
F. I. Ghuloum, L. A. Stevens, C. A. Johnson, N. A. Riobo-Del Galdo, M. H. Amer
This study shows that topographically-textured microparticles activate Hedgehog signaling and induce osteogenesis in mesenchymal stem cells without exogenous factors.
bioRxiv · Jul 19, 2023Bioengineering