The extracellular gate shapes the energy profile of an ABC exporter
C. A. J. Hutter, M. H. Timachi, L. M. Hürlimann, I. Zimmermann, P. Egloff, H. Göddeke, S. Kucher, S. Stefanic, M. Karttunen, L. V. Schäfer, E. Bordignon, M. A. Seeger
This study uses a synthetic antibody to determine the structure and mechanism of an ABC exporter's extracellular gate, showing its role in ATPase activity and transport.
bioRxiv · Sep 18, 2018Biochemistry