Author

M. Heddes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Assay:metabolomics· 2 Assay:metagenomics· 2

Frequent Co-Authors

D. Haller· 4 shared K. Kleigrewe· 4 shared S. Kiessling· 4 shared B. Altaha· 3 shared Y. Niu· 3 shared C. Meng· 2 shared M. Gigl· 2 shared S. Reitmeier· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersPhysiology

D. Haller

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Diurnal rhythmicity of fecal microbiota and metabolite profiles in the first year of life: a randomized controlled interventional trial with infant formula

N. Heppner, S. Reitmeier, M. Heddes, M. Vig Merino, L. Schwartz, A. Dietrich, M. List, M. Gigl, C. Meng, H. Omer, K. Kleigrewe, D. R. van der Veen, M. Schirmer, S. Kiessling, D. Haller

This study shows that microbiota and metabolite rhythmicity develops early in life, influenced by diet and breastfeeding, with GOS-supplemented formula promoting bifidobacteria.

bioRxiv · Oct 19, 2023 · PreprintMicrobiology

Targeting the intestinal circadian clock by meal timing ameliorates gastrointestinal inflammation

Y. Niu, M. Heddes, B. Altaha, M. Birkner, K. Kleigrewe, C. Meng, D. Haller, S. Kiessling

This study shows that altering meal timing (restricted feeding) can restore intestinal clock function and reduce inflammation in IBD models.

bioRxiv · Jan 24, 2023Physiology

Genetic and environmental circadian disruption induce metabolic impairment through changes in the gut microbiome

B. Altaha, M. Heddes, V. Pilorz, Y. Niu, E. Gorbunova, M. Gigl, K. Kleigrewe, H. Oster, D. Haller, S. Kiessling

This study shows that circadian disruption from genetic and environmental factors causes metabolic issues by altering gut microbiome function and rhythmicity.

bioRxiv · Jul 27, 2022 · PreprintPhysiology

The intestinal circadian clock drives microbial rhythmicity to maintain gastrointestinal homeostasis

M. Heddes, B. Altaha, Y. Niu, S. Reitmeier, K. Kleigrewe, D. Haller, S. Kiessling

This study shows that the host's intestinal circadian clock regulates microbial rhythms, maintaining gut homeostasis through metabolite production and immune system modulation.

bioRxiv · Oct 18, 2021Physiology