Histone Lactylation Drives CD8 T Cell Metabolism and Function
D. Raychaudhuri, P. Singh, M. Hennessey, B. Chakraborty, A. J. Tannir, A. Trujillo-Ocampo, J. S. Im, S. Goswami
This study shows histone lactylation, specifically H3K18la and H3K9la, modulates CD8 T cell metabolism and function, impacting anti-tumor immunity.
bioRxiv · Aug 25, 2023Immunology