Lack of Tgfbr1 and Acvr1b synergistically stimulates myofibre hypertrophy and accelerates muscle regeneration
M. Hillege, A. Shi, R. A. Galli, G. Wu, P. Bertolino, W. M. Hoogaars, R. T. Jaspers
This study shows that simultaneous knockout of Tgfbr1 and Acvr1b in muscle leads to hypertrophy and enhanced regeneration, but not when only one receptor is knocked out.
bioRxiv · Mar 3, 2021Physiology