BiochemistrybioRxiv
Cryo-EM structures capturing the entire transport cycle of the P4-ATPase flippase
M. Hiraizumi, K. Yamashita, T. Nishizawa, O. Nureki
The paper reports cryo-EM structures of six intermediates in the ATP8A1-CDC50a flippase cycle, revealing the mechanism of phospholipid translocation.