Author

M. Holford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Animal Behavior & Cognition· 1 Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1 Evolutionary Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1

Frequent Co-Authors

P. Anand· 3 shared T. Napolitano· 2 shared A. B. Braunschweig· 1 shared A. Claridge-Chang· 1 shared A. Eriksson· 1 shared A. R. Cerullo· 1 shared A. Riesgo· 1 shared A. Verdes· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBioengineering

P. Anand

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Towards the identification of the molecular toolkit involved in scale worm bioluminescence (Polinoidae, Annelida)

C. Gracia-Sancha, M. Conejero, S. Taboada, D. Martin, A. Riesgo, M. Holford, A. Verdes

The paper identifies 16 candidate genes and 12 enriched GO terms potentially involved in bioluminescence in scale worms using RNA-seq and histological analyses.

bioRxiv · Jan 28, 2024 · PreprintEvolutionary Biology

Discovering venom-derived drug candidates using differential gene expression

J. D. Romano, H. Li, T. Napolitano, R. Realubit, C. Karan, M. Holford, N. Tatonetti

This study introduces VenomSeq, a platform that uses transcriptomics and differential gene expression to link venoms to drugs and diseases, generating new therapeutic hypotheses.

bioRxiv · Jun 1, 2023Pharmacology & Toxicology

Comparative Mucomic Analysis of Three Functionally Distinct Cornu aspersum Secretions

A. R. Cerullo, M. McDermott, L. E. Pepi, Z.-L. Liu, D. Barry, S. Zhang, X. Chen, P. Azadi, M. Holford, A. B. Braunschweig

This study compares the composition and properties of three mucus types from Cornu aspersum to understand their structure-function relationships and identify novel components.

bioRxiv · Nov 16, 2022 · PreprintBiochemistry

Induced Disassembly of a Virus-Like Particle under Physiological Conditions for Venom Peptide Delivery

M. Holford, T. Napolitano, P. Anand, J. S. K. Ho, S. Jabeen, J. Kuppan, S. Manir, M. P. Kelly

This paper develops a method to induce disassembly of virus-like particles under physiological conditions for delivering venom peptides.

bioRxiv · Sep 1, 2020Bioengineering

Antitumor effects of Tv1 venom peptide in liver cancer

P. Anand, P. Filipenko, J. Huaman, M. Lyudmer, M. Hossain, C. Santamaria, K. Huang, O. Ogunwobi, M. Holford

This study shows that Tv1, a venom peptide from Terebra variegata, inhibits liver cancer cell proliferation and reduces tumor size in mice by targeting TRP channels and downregulating COX-2.

bioRxiv · Jan 26, 2019 · PreprintCancer Biology

Using Drosophila behavioral assays to characterize terebrid venom-peptide bioactivity

A. Eriksson, P. Anand, J. Gorson, C. Grijuc, E. Hadelia, J. Stewart, M. Holford, A. Claridge-Chang

This study uses Drosophila behavioral assays to assess the bioactivity of two terebrid venom peptides, finding distinct effects on pain and food intake.

bioRxiv · Aug 13, 2018Animal Behavior & Cognition