Modular assembly of the nucleolar large subunit processome
Z. Assur Sanghai, L. Miller, K. R. Molloy, J. Barandun, M. Hunziker, M. Chaker-Margot, J. Wang, B. T. Chait, S. Klinge
The paper determines cryo-EM structures of the nucleolar large subunit processome in different states, revealing how assembly factors prevent premature folding and enable distinct folding pathways.
bioRxiv · Nov 21, 2017Biochemistry