Cancer BiologybioRxiv
Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking LAIR-collagen interaction
M. I. P. Ramos, L. Tian, E. J. de Ruiter…·L. Meyaard
The paper demonstrates that NC410, a LAIR-2 Fc protein, blocks LAIR-1-collagen interaction, enhancing T cell activity and reducing tumor growth in humanized models.
DOI 10.7554/elife.62927