Increased autophagy in ephrinB2 deficient osteocytes is associated with hypermineralized, brittle bones
C. Vrahnas, T. A. Dite, N. Ansari, B. Crimeen-Irwin, H. Nguyen, M. R. Forwood, Y. Hu, M. Ikegame, K. R. Bambery, C. Petibois, M. J. Tobin, G. K. Smyth, J. S. Oakhill, T. J. Martin, N. A. Sims
This study shows that ephrinB2 deficiency in osteocytes increases autophagy, leading to accelerated secondary mineralization and brittle bones.
bioRxiv · Mar 1, 2018Cell Biology