Author

B. Crimeen-Irwin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

I. J. Poulton· 2 shared J. H. Gooi· 2 shared N. A. Sims· 2 shared N. Ansari· 2 shared N. E. McGregor· 2 shared T. J. Martin· 2 shared C. Petibois· 1 shared C. S. Kovacs· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersPathology

I. J. Poulton

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Author profile →

3 papers

Recent·Most cited

The effect of carbamazepine on bone structure and strength in control and Osteogenesis Imperfecta (Col1a2 +/p.G610C) mice

M. Blank, N. E. McGregor, L. Rowley, L. H. Kung, B. Crimeen-Irwin, I. J. Poulton, E. C. Walker, J. H. Gooi, S. R. Lamande, N. Sims, J. F. Bateman

This study tests carbamazepine's effect on bone structure and strength in OI mice and controls, finding no benefit in OI mice but growth impairment in controls.

bioRxiv · Feb 23, 2022Pathology

Dmp1Cre-directed knockdown of PTHrP in murine decidua is associated with increased bone width and a life-long increase in strength specific to male progeny

N. Ansari, T. Isojima, B. Crimeen-Irwin, I. J. Poulton, N. E. McGregor, P. M. Ho, C. S. Kovacs, E. Dimitriadis, J. H. Gooi, T. J. Martin, N. A. Sims

The paper shows that knocking down PTHrP in murine decidua via Dmp1Cre leads to increased bone width and strength in male offspring, suggesting a maternal influence on bone development.

bioRxiv · Jun 9, 2020Cell Biology

Increased autophagy in ephrinB2 deficient osteocytes is associated with hypermineralized, brittle bones

C. Vrahnas, T. A. Dite, N. Ansari, B. Crimeen-Irwin, H. Nguyen, M. R. Forwood, Y. Hu, M. Ikegame, K. R. Bambery, C. Petibois, M. J. Tobin, G. K. Smyth, J. S. Oakhill, T. J. Martin, N. A. Sims

This study shows that ephrinB2 deficiency in osteocytes increases autophagy, leading to accelerated secondary mineralization and brittle bones.

bioRxiv · Mar 1, 2018Cell Biology